Table 3 Significant differences between cases and controls for some variants
Variant | Cases | Controls | P value | Odds ratio (95% CI) | ||
|---|---|---|---|---|---|---|
rs1050631 | ||||||
Genotype (No.) | CC (reference) | 88 | 71 | |||
CT | 55 | 70 | < 0.0001 | 3.37 (2.16–5.27) | ||
TT | 7 | 9 | 0.019 | 3.4 (1.22–9.49) | ||
CT+TT | 62 | 79 | < 0.0001 | 3.374 (2.19–5.19) | ||
rs12983273 | ||||||
Genotype (No.) | CC (reference) | 128 | 113 | |||
CT+TT | 22 | 37 | 0.031 | 1.9 (1.1–3.4) | ||
Allele (Freq.) | C (reference) | 0.923 | 0.863 | |||
T | 0.077 | 0.137 | 0.02 | 1.91 (1.1–3.3) | ||
rs1695 | ||||||
Genotype (No.) | AA (reference) | 56 | 74 | |||
AG+GG | 94 | 76 | 0.036 | 0.612 (0.39–0.97) | ||
Allele (Freq.) | A (reference) | 0.627 | 0.703 | |||
G | 0.373 | 0.297 | 0.047 | 0.708 (0.5–0.99) | ||
rs2274223 | ||||||
Genotype (No.) | AA (reference) | 34 | 47 | |||
GG | 36 | 24 | 0.035 | 0.482 (0.24–0.95) | ||
rs2292832 | ||||||
Genotype (No.) | TT (reference) | 68 | 45 | |||
TC | 58 | 65 | 0.046 | 1.693 (1.01–2.84) | ||
CC | 27 | 40 | 0.01 | 2.239 (1.21–4.15) | ||
TC+CC | 85 | 105 | 0.01 | 1.867 (1.16–3) | ||
Allele (Freq.) | T (reference) | 0.647 | 0.517 | |||
C | 0.353 | 0.483 | 0.001 | 1.712 (1.23–2.38) | ||
rs2505901 | ||||||
Genotype (No.) | TT (reference) | 88 | 71 | |||
TC+CC | 62 | 79 | 0.0497 | 1.58 (1.0005–2.5) | ||
Allele (Freq.) | T (reference) | 0.717 | 0.637 | |||
C | 0.283 | 0.363 | 0.0366 | 1.44 (1.02–2.04) | ||
rs33927012 | ||||||
Allele (Freq.) | T (reference) | 0.933 | 0.97 | |||
C | 0.067 | 0.03 | 0.0412 | 0.43 (0.19–0.97) | ||
rs3745469 | ||||||
Genotype (No.) | GG (reference) | 80 | 97 | |||
GA+AA | 70 | 53 | 0.046 | 0.62 (0.39–0.99) | ||
Allele (Freq.) | G (reference) | 0.72 | 0.79 | |||
A | 0.28 | 0.21 | 0.047 | 0.68 (0.47–0.99) | ||
rs6505162 | ||||||
Genotype (No.) | AA (reference) | 19 | 34 | |||
AC | 73 | 60 | 0.02 | 0.46 (0.24–0.89) | ||
AC+CC | 131 | 116 | 0.025 | 0.5 (0.27–0.91) |