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Table 5 Distribution of the response of GBM patients when IDH1 mutation and MGMT methylation were combined

From: Clinical impact of IDH1 mutations and MGMT methylation in adult glioblastoma

Response

Either IDH1 mutated or MGMT methylated or both are not detected (n = 43)

IDH1 mutation with MGMT methylation (n = 15)

Responders (n = 30)

15 (34.9%)

15 (100%)

Non-responders (n = 28)

28 (65.1%)

0 (0%)

Statistics

X2 = 18.89, P < 0.0001