Skip to main content
Egyptian Journal of Medical Human Genetics

Table 4 Intermolecular interactions between Rab39a and natural substrate

From: Computer-aided identification of lung cancer inhibitors through homology modeling and virtual screening

 

Binding residues

Distance of H-bonds (A°)

H-bonds

CYS41:SG - B:ASN849:O

1.82

CYS41:SG - B:ASN849:OD1

2.36

SER51:N - B:THR975:OG1

2.87

SER51:OG - B:GLU973:OE2

1.87

ARG61:NH2 - B:ASN970:OD1

2.56

LYS63:NZ - B:GLU973:OE1

1.96

LYS63:NZ - B:GLU973:OE2

2.82

ASN849:ND2 - :VAL45:O

2.78

Pi-cation

PHE49 - B:ARG1008:NH1

6.51

PHE49 - B:ARG1008:NH2

4.56

Pi-sigma

B:HIS933 - :PHE49:CE2

3.19

  1. CYS41, VAL45, PHE49, SER51, ARG61 and LYS63 residues in Rab39a bind with natural substrate DENND5B, analysed using Discovery studio
Back to article page