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Table 2 VDR gene polymorphism genotype and allele frequencies in the two study groups

From: Protective association of VDR gene polymorphisms and haplotypes with multiple sclerosis patients in Egyptian population

SNP MS (n = 50) Controls (n = 50) Significance OR (95% CI)
No. % No. %
FokI
 FF (wt) 36 72.0 25 50.0 χ2 = 6.33* 0.42 (0.26–0.85)
 Ff (ht) 14 28.0 22 44.0 MCp = 0.029*
 ff (mut) 0 0.0 3 6.0  
 F 86 86.0 72 72.0 χ2 = 5.91*
 f 14 14.0 28 28.0 P = 0.015*
BsmI
 BB (mut) 20 40.0 22 44.0 χ2 = 1.24 1.33 (0.76–2.32)
 Bb (ht) 12 24.0 15 30.0 P = 0.54
 bb (wt) 18 36.0 13 26.0  
 B 52 52.0 59 59.0 χ2 = 0.99
 b 48 48.0 41 41.0 P = 0.32
ApaI
 AA (mut) 20 40.0 36 72.0 χ2 = 11.103* 2.47 (1.25–4.88)
 Aa (ht) 28 56.0 12 24.0 MCp = 0.002*
 aa (wt) 2 4.0 2 4.0  
 A 68 68.0 84 84.0 χ2 = 7.02*
 a 32 32.0 16 16.0 P = 0.008*
TaqI
 TT (wt) 24 48.0 18 36.0 χ2 = 4.16 0.55 (0.31–0.98)
 Tt (ht) 20 40.0 18 36.0 P = 0.13
 tt (mut) 6 12.0 14 28.0  
 T 68 68.0 54 54.0 χ2 = 4.12*
 t 32 32.0 46 46.0 P = 0.04*
Tru9I
 UU (wt) 28 56.0 37 74.0 χ2 = 4.80 1.66 (0.82–3.35)
 Uu (ht) 20 40.0 10 20.0 MCp = 0.11
 uu (mut) 2 4.0 3 6.0  
 U 76 76.0 84 84.0 χ2 = 2.0
 u 24 24.0 16 16.0 P = 0.16
  1. wt homozygote wild type, ht heterozygote mutated, mut homozygote mutated, SNP single nucleotide polymorphism, MCp Monte Carlo test, χ2 chi-square test, OR odds ratio, CI 95% 95% confidence interval
  2. *Significant at P ≤ 0.05