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Table 4 Association of biallelic haplotypes BsmI/ApaI, Tru9I/ApaI, FokI/ApaI, FokI/TaqI, and BsmI/TaqI in the two study groups

From: Protective association of VDR gene polymorphisms and haplotypes with multiple sclerosis patients in Egyptian population

Haplotype Haplotype frequencies (%) OR (95% CI)
MS (n = 50) Controls (n = 50)
BsmI/ApaI
 BA 0.44 0.58 1
 Ba 0.08 0.01 10.55* (1.27–87.46)
 bA 0.24 0.26 1.22 (0.62–2.4)
 ba 0.24 0.15 2.11 (0.99–4.49)
Tru9I/ApaI
 UA 0.56 0.71 1
 Ua 0.20 0.13 1.95 (0.89–4.26)
 uA 0.12 0.13 1.17 (0.50–2.76)
 ua 0.12 0.03 5.07* (1.36–18.85)
FokI/ApaI
 FA 0.62 0.65 1
 Fa 0.24 0.07 3.59* (1.45–8.94)
 fA 0.06 0.19 0.331* (0.124–0.884)
 fa 0.08 0.09 0.932 (0.338–2.57)
FokI/TaqI
 FT 0.60 0.46 1
 Ft 0.26 0.26 0.77 (0.39–1.492)
 fT 0.08 0.08 0.77 (0.27–2.20)
 ft 0.06 0.20 0.23* (0.09–0.62)
BsmI/TaqI
 BT 0.32 0.26 1
 Bt 0.20 0.33 0.49 (0.23–1.05)
 bT 0.36 0.28 1.05 (0.51–2.14)
 bt 0.12 0.13 0.75 (0.29–1.92)
  1. OR odds ratio, 95% CI 95% confidence interval, NA not applicable