Table 4 Association of biallelic haplotypes BsmI/ApaI, Tru9I/ApaI, FokI/ApaI, FokI/TaqI, and BsmI/TaqI in the two study groups
Haplotype | Haplotype frequencies (%) | OR (95% CI) | |
|---|---|---|---|
MS (n = 50) | Controls (n = 50) | ||
BsmI/ApaI | |||
BA | 0.44 | 0.58 | 1 |
Ba | 0.08 | 0.01 | 10.55* (1.27–87.46) |
bA | 0.24 | 0.26 | 1.22 (0.62–2.4) |
ba | 0.24 | 0.15 | 2.11 (0.99–4.49) |
Tru9I/ApaI | |||
UA | 0.56 | 0.71 | 1 |
Ua | 0.20 | 0.13 | 1.95 (0.89–4.26) |
uA | 0.12 | 0.13 | 1.17 (0.50–2.76) |
ua | 0.12 | 0.03 | 5.07* (1.36–18.85) |
FokI/ApaI | |||
FA | 0.62 | 0.65 | 1 |
Fa | 0.24 | 0.07 | 3.59* (1.45–8.94) |
fA | 0.06 | 0.19 | 0.331* (0.124–0.884) |
fa | 0.08 | 0.09 | 0.932 (0.338–2.57) |
FokI/TaqI | |||
FT | 0.60 | 0.46 | 1 |
Ft | 0.26 | 0.26 | 0.77 (0.39–1.492) |
fT | 0.08 | 0.08 | 0.77 (0.27–2.20) |
ft | 0.06 | 0.20 | 0.23* (0.09–0.62) |
BsmI/TaqI | |||
BT | 0.32 | 0.26 | 1 |
Bt | 0.20 | 0.33 | 0.49 (0.23–1.05) |
bT | 0.36 | 0.28 | 1.05 (0.51–2.14) |
bt | 0.12 | 0.13 | 0.75 (0.29–1.92) |