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Table 5 Association of tri-allelic haplotypes in the two study groups

From: Protective association of VDR gene polymorphisms and haplotypes with multiple sclerosis patients in Egyptian population

Haplotype

Haplotype frequencies (%)

OR (95% CI)

MS (n = 50)

Controls (n = 50)

BsmI/Tru9I/ApaI

 BUA

0.38

0.52

1

 BUa

0.04

0

NA (NA)

 BuA

0.06

0.06

1.37 (0.41–4.57)

 Bua

0.04

0.01

5.47 (0.59–50.95)

 bUA

0.18

0.19

1.30 (0.60–2.80)

 bUa

0.16

0.13

1.68 (0.72–3.91)

 buA

0.06

0.07

1.17 (0.36–3.77)

 bua

0.08

0.02

5.47 (1.10–27.25)

FokI/ApaI/TaqI

 FAT

0.46

0.40

1

 FAt

0.16

0.25

0.56 (0.26–1.19)

 FaT

0.14

0.06

2.03 (0.71–5.78)

 Fat

0.10

0.01

8.70 (1.07–70.93)

 fAT

0.02

0.02

0.87 (0.117–6.46)

 fAt

0.04

0.17

0.20 (0.06–0.66)

 faT

0.06

0.06

0.87 (0.26–2.91)

 fat

0.02

0.03

0.58 (0.09–3.65)

BsmI/ApaI/TaqI

 BAT

0.28

0.25

1

 BAt

0.16

0.33

0.43 (0.19–0.97)

 BaT

0.04

0.01

3.57 (0.37–34.11)

 Bat

0.04

0

NA (NA)

 bAT

0.20

0.17

1.05 (0.45–2.44)

 bAt

0.04

0.09

0.40 (0.11–1.45)

 baT

0.16

0.11

1.30 (0.51–3.32)

 bat

0.08

0.04

1.79 (0.48–6.66)

  1. OR odds ratio, 95% CI 95% confidence interval, NA not applicable