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Table 5 Association of tri-allelic haplotypes in the two study groups

From: Protective association of VDR gene polymorphisms and haplotypes with multiple sclerosis patients in Egyptian population

Haplotype Haplotype frequencies (%) OR (95% CI)
MS (n = 50) Controls (n = 50)
BsmI/Tru9I/ApaI
 BUA 0.38 0.52 1
 BUa 0.04 0 NA (NA)
 BuA 0.06 0.06 1.37 (0.41–4.57)
 Bua 0.04 0.01 5.47 (0.59–50.95)
 bUA 0.18 0.19 1.30 (0.60–2.80)
 bUa 0.16 0.13 1.68 (0.72–3.91)
 buA 0.06 0.07 1.17 (0.36–3.77)
 bua 0.08 0.02 5.47 (1.10–27.25)
FokI/ApaI/TaqI
 FAT 0.46 0.40 1
 FAt 0.16 0.25 0.56 (0.26–1.19)
 FaT 0.14 0.06 2.03 (0.71–5.78)
 Fat 0.10 0.01 8.70 (1.07–70.93)
 fAT 0.02 0.02 0.87 (0.117–6.46)
 fAt 0.04 0.17 0.20 (0.06–0.66)
 faT 0.06 0.06 0.87 (0.26–2.91)
 fat 0.02 0.03 0.58 (0.09–3.65)
BsmI/ApaI/TaqI
 BAT 0.28 0.25 1
 BAt 0.16 0.33 0.43 (0.19–0.97)
 BaT 0.04 0.01 3.57 (0.37–34.11)
 Bat 0.04 0 NA (NA)
 bAT 0.20 0.17 1.05 (0.45–2.44)
 bAt 0.04 0.09 0.40 (0.11–1.45)
 baT 0.16 0.11 1.30 (0.51–3.32)
 bat 0.08 0.04 1.79 (0.48–6.66)
  1. OR odds ratio, 95% CI 95% confidence interval, NA not applicable