Skip to main content
Egyptian Journal of Medical Human Genetics

Table 10 Genotype distribution of MTHFR and serum levels of vitamin B12, folate, and homocysteine in DSM and CM

From: MTHFR gene polymorphism and associated nutritional deficiency in the etiology and pathogenesis of Down syndrome

Serum

CM

DSM

CC

CT

CC

CT

Vitamin B12

383.9 ± 49.35

375.5 ± 41.14NS

232.3 ± 28.11#

121.4 ± 10.11***++

Folic acid

6.444 ± 0.6534

4.117 ± 0.6469NS

3.578 ± 0.3562##

2.044 ± 0.2161*++

Homocysteine

4.11 ± 1.116

17.05 ± 2.979NS

20.38 ± 2.329###

32.53 ± 3.878**+++

  1. #CM vs DSM (CC/CC), #p < 0.05), ##p < 0.01, ###p < 0.001
  2. *CM Vs DSM (CT/CT), *p < 0.05, **p < 0.01, ***p < 0.001
  3. +DSM (CC Vs CT), +p < 0.05), ++p < 0.01, +++p < 0.001, NS CM (CC/CT), not significant
Back to article page