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Table 7 Genotype distribution of MTHFR in DSM and birth weight in the DS child

From: MTHFR gene polymorphism and associated nutritional deficiency in the etiology and pathogenesis of Down syndrome

Genotype

DSM group

Normal

n, f(%)

LBW

n, f(%)

OR (CI)

p value

CC

28 (23.7)

14 (11.8)

Reference

Reference

CT

23 (19.4)

53 (44.9)

4.609 (2.0 to10.3)

p < 0.001***

  1. n number of genotype, f frequency, OR odds ratio, CI 95% confidence interval
  2. ***p < 0.001