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Table 2 Genotype and allele frequencies of APOE ε, rs439401, and rs4420638 in case and control groups

From: Association study of APOE gene polymorphisms with diabetes and the main cardiometabolic risk factors, in the Algerian population

  MetS Non-MetS
Epsilon   
 Genotype frequency N(%)   
  ε2/ε2 1(0.7) 5(0.9)
  ε2/ε3 14(9.7) 43(7.4)
  ε2/ε4 0 3(0.5)
  ε3/ε3 109(75.7) 457(78.8)
  ε3/ε4 16(11.1) 66(11.4)
  ε4/ε4 4(2.8) 6(1)
 Total 144(100) 580(100)
 pEHW 0.77 0.68
 Allele frequency (%)   
  ε2 5.5 4.8
  ε3 86.1 88.2
  ε4 8.4 7
rs439401   
 Genotype frequency N(%)   
  CC 56(38.6) 228(39.1)
  CT 65(44.8) 265(45.2)
  TT 24(16.6) 90(15.4)
 Total 145(100) 583(100)
 pEHW 0.48 0.79
 Allele frequency (%)   
  C 61 62
  T 39 38
rs4420638   
 Genotype frequency N(%)   
  AA 117(79.6) 473(79.1)
  AG 27(18.4) 118(19.7)
  GG 3(2) 7(1.2)
 Total 147(100) 598(100)
 pEHW 0.90 0.14
 Allele frequency (%)   
  A 88.8 89
  G 11.2 11
  1. H-W Hardy-Weinberg equilibrium