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Table 2 Genotype and allele frequencies of APOE ε, rs439401, and rs4420638 in case and control groups

From: Association study of APOE gene polymorphisms with diabetes and the main cardiometabolic risk factors, in the Algerian population

 

MetS

Non-MetS

Epsilon

  

 Genotype frequency N(%)

  

  ε2/ε2

1(0.7)

5(0.9)

  ε2/ε3

14(9.7)

43(7.4)

  ε2/ε4

0

3(0.5)

  ε3/ε3

109(75.7)

457(78.8)

  ε3/ε4

16(11.1)

66(11.4)

  ε4/ε4

4(2.8)

6(1)

 Total

144(100)

580(100)

 pEHW

0.77

0.68

 Allele frequency (%)

  

  ε2

5.5

4.8

  ε3

86.1

88.2

  ε4

8.4

7

rs439401

  

 Genotype frequency N(%)

  

  CC

56(38.6)

228(39.1)

  CT

65(44.8)

265(45.2)

  TT

24(16.6)

90(15.4)

 Total

145(100)

583(100)

 pEHW

0.48

0.79

 Allele frequency (%)

  

  C

61

62

  T

39

38

rs4420638

  

 Genotype frequency N(%)

  

  AA

117(79.6)

473(79.1)

  AG

27(18.4)

118(19.7)

  GG

3(2)

7(1.2)

 Total

147(100)

598(100)

 pEHW

0.90

0.14

 Allele frequency (%)

  

  A

88.8

89

  G

11.2

11

  1. H-W Hardy-Weinberg equilibrium