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Table 5 APOE rs439401 polymorphism and cardiometabolic risk

From: Association study of APOE gene polymorphisms with diabetes and the main cardiometabolic risk factors, in the Algerian population

rs439401 Major allele/minor allele ISOR
   Genotypes (N)
p
OR [95% CI]
p
OR* [95% CI]
p
T2D C/T Control Case CT vs CC:
1.57 [0.88–2.79]
p = 0.13
TT vs CC:
2.12 [1.02–4.39]
p = 0.04
1.47 [1.03–2.09]
p = 0.03
CC (254)
CT (285)
TT (95)
CC (22)
CT (38)
TT (16)
p = 0.13  
Obesity C/T CC (233)
CT (262)
TT (89)
CC (57)
CT (74)
TT (26)
CA vs CC:
1.27 [0.84–1.92]
p = 0.26
AA vs CC:
1.34 [0.76–2.35]
p = 0.31
1.16 [0.89–1.51]
p = 0.27
p = 0.71  
MetS C/T CC (228)
CT (265)
TT (90)
CC (56)
CT (65)
TT (24)
AT vs AA:
1.04 [0.68–1.59]
p = 0.87
TT vs AA:
1.13 [0.64–2.02]
p = 0.67
1.06 [0.80–1.40]
p = 0.69
p = 0.95
HBP C/T CC (241)
CT (262)
TT (86)
CC (49)
CT (74)
TT (29)
CT vs CC:
1.46 [0.95–2.26]
p = 0.09
TT vs CC:
1.90 [1.07–3.36]
p = 0.03
1.46 [1.12–1.90]
p = 0.006*
p = 0.11  
  1. T2D type 2 diabetes, MetS metabolic syndrome, HBP high blood pressure. OR adjusted on age, gender, physical activity, and smoking status. OR* obtained for additive model. p values were adjusted for age, gender, physical activity, and smoking status. Significant p values are indicated in italics with an asterisk