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Table 4 Flow-cytometric results of B and T lymphocyte subsets and NK cells in the studied patients

From: Screening for B cell, T cell and natural killer cell defects among children with methylmalonic and propionic acidemias

T lymphocyte subsets

Mean ± SD

Range

Interpretation

CD3+ (%)

68.13 ± 10.62

43.5–84.9

Normal

26 (86.7%)

Low

4 (13.3%)

CD3+ (absolute) cells/mm3

2469.63 ± 1921.90

414–7668

Normal

16 (53.3%)

Low

14 (46.7%)

CD4+ (%)

57.11 ± 15.33

24.9–83.3

Normal

29 (96.7%)

Low

1 (3.3%)

CD4+ (absolute) cells/mm3

2119.67 ± 1654.29

190–6073

Normal

21 (70.0%)

Low

9 (30.0%)

CD8+ (%)

35.23 ± 13.47

13.6–66.7

Normal

29 (96.7%)

Low

1 (3.3%)

CD8+ (absolute) cells/mm3

1107.37 ± 817.89

257–2838

Normal

22 (73.3%)

Low

8 (26.7%)

CD4/CD8 ratio

2.11 ± 1.48

0.37–6.12

Normal

18 (60.0%)

Low

12 (40.0%)

CD56+ (%)

9.15 ± 5.86

2.22–23.7

Normal

25 (83.3%)

Low

5 (16.7%)

CD56+ (absolute) cells/mm3

393.30 ± 453.79

18–2160

Normal

22 (73.3%)

Low

8 (26.7%)

CD19+ (%)

7.90 ± 3.90

2.18–14.3

Normal

1 (3.3%)

Low

29 (96.7%)

CD19+ (absolute) cells/mm3

414.15 ± 246.01

37.06–930

Normal

13 (43.3%)

Low

17 (56.7%)

CD27+ (%)

33.61 ± 17.11

8–65

Normal

4 (13.3%)

High

26 (86.7%)

CD27+ (absolute) cells/mm3

134.64 ± 103.57

10.98–413.54

Normal

25 (83.3%)

Low

5 (16.7%)

  1. CD cluster of differentiation, % percentage, MMA methylmalonic acidemia, PA propionic acidemia, SD standard deviation