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Table 7 Variation of T and B lymphocyte subsets and NK cells among metabolically controlled and uncontrolled patients

From: Screening for B cell, T cell and natural killer cell defects among children with methylmalonic and propionic acidemias

T lymphocyte subsets

Controlled (N = 18)

Uncontrolled (N = 12)

Comparison

χ 2

p value

N

%

N

%

CD3+ (%)

Normal

15

83.3

11

91.7

0.433

0.511

Low

3

16.7

1

8.3

CD3+ count cells/mm3

Normal

9

50.0

7

58.3

0.201

0.654

Low

9

50.0

5

41.7

CD4+ (%)

Normal

17

94.4

12

100.0

0.690

0.406

Low

1

5.6

0

0.0

CD4+ count cells/mm3

Normal

11

61.1

10

83.3

1.693

0.193

Low

7

38.9

2

16.7

CD8+ (%)

Normal

18

100.0

11

91.7

1.552

0.213

Low

0

0.0

1

8.3

CD8+ count cells/mm3

Normal

13

72.2

9

75.0

0.028

0.866

Low

5

27.8

3

25.0

CD4/CD8 ratio

Normal

11

61.1

7

58.3

0.023

0.879

Low

7

38.9

5

41.7

CD56+ (%)

Normal

16

88.9

9

75.0

1.000

0.317

Low

2

11.1

3

25.0

CD56+ count cells/mm3

Normal

13

72.2

9

75.0

0.028

0.866

Low

5

27.8

3

25.0

CD19+ (%)

Normal

0

0

1

8.3

1.42

0.4

Low

18

100

11

91.7

CD19+ count cells/mm3

Normal

7

38.9

6

50

0.362

0.410

Low

11

61.1

6

50

CD27+ (%)

Normal

4

22.2

0

0

3.077

0.112

Low

14

77.8

12

100

  1. CD cluster of differentiation, mm millimeter, N number, % percentage