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Table 7 Variation of T and B lymphocyte subsets and NK cells among metabolically controlled and uncontrolled patients

From: Screening for B cell, T cell and natural killer cell defects among children with methylmalonic and propionic acidemias

T lymphocyte subsets Controlled (N = 18) Uncontrolled (N = 12) Comparison
χ 2 p value
N % N %
CD3+ (%) Normal 15 83.3 11 91.7 0.433 0.511
Low 3 16.7 1 8.3
CD3+ count cells/mm3 Normal 9 50.0 7 58.3 0.201 0.654
Low 9 50.0 5 41.7
CD4+ (%) Normal 17 94.4 12 100.0 0.690 0.406
Low 1 5.6 0 0.0
CD4+ count cells/mm3 Normal 11 61.1 10 83.3 1.693 0.193
Low 7 38.9 2 16.7
CD8+ (%) Normal 18 100.0 11 91.7 1.552 0.213
Low 0 0.0 1 8.3
CD8+ count cells/mm3 Normal 13 72.2 9 75.0 0.028 0.866
Low 5 27.8 3 25.0
CD4/CD8 ratio Normal 11 61.1 7 58.3 0.023 0.879
Low 7 38.9 5 41.7
CD56+ (%) Normal 16 88.9 9 75.0 1.000 0.317
Low 2 11.1 3 25.0
CD56+ count cells/mm3 Normal 13 72.2 9 75.0 0.028 0.866
Low 5 27.8 3 25.0
CD19+ (%) Normal 0 0 1 8.3 1.42 0.4
Low 18 100 11 91.7
CD19+ count cells/mm3 Normal 7 38.9 6 50 0.362 0.410
Low 11 61.1 6 50
CD27+ (%) Normal 4 22.2 0 0 3.077 0.112
Low 14 77.8 12 100
  1. CD cluster of differentiation, mm millimeter, N number, % percentage