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Table 2 Serum level of TLR-7 in urinary bladder cancer and urinary tract infection patients and control distributed according to some characteristics

From: Serum level and single-nucleotide polymorphisms of toll-like receptor-7 among urinary bladder cancer Iraqi patients

Characteristic Median (range); ng/ml p (pc)
UBC (N = 66) UTI (N = 40) C (N = 48) UBC vs. C UTI vs. C UBC vs. UTI
Total 1.4 (0.1–22.2) 8.1 (0.7–14.6) 9.5 (1.9–25.1) < 0.001 (S) 0.089 (NS) < 0.001 (S)
Gender
 Male 1.3 (0.1–22.1) 7.1 (4.1–14.6) 6.5 (1.9–25.1) < 0.001 (S) 0.564 (NS) < 0.001 (S)
 Female 1.6 (0.6–3.4) 8.5 (0.7–14.5) 11.7 (5.6–17.0) < 0.001 (S) 0.003 (S) 0.001 (S)
p (pc) 0.827 (NS) 0.654 (NS) 0.002 (S)    
Age group
 < 48 years 2.0 (0.1–22.2) 8.3 (0.9–14.6) 9.1 (1.9–25.1) < 0.001 (S) 0.199 (NS) < 0.001 (S)
 ≥ 48 years 1.1 (0.1–9.2) 7.2 (0.7–14.5) 10.4 (6.9–13.9) < 0.001 (S) 0.343 (NS) < 0.001 (S)
p (pc) 0.152 (NS) 0.919 (NS) 0.559 (NS)    
Cigarette-smoking
 Yes 1.3 (0.1–22.2) 7.1 (4.1–10.8) 8.8 (1.9–25.1) < 0.001 (S) 0.387 (NS) < 0.001 (S)
 No 1.6 (0.1–7.9) 8.5 (0.7–14.6) 10.1 (2.9–17.0) < 0.001 (S) 0.134 (NS) < 0.001 (S)
p (pc) 0.933 (NS) 0.754 (NS) 0.668 (NS)    
Alcohol-consuming
 Yes 2.7 (0.1–9.8) 7.0 (6.8.2–7.2) 4.6 (1.9–7.2) 0.309 (NS) 0.533 (NS) 0.173 (NS)
 No 1.1 (0.1–22.2) 8.3 (0.7–14.6) 10.4 (2.0–25.1) < 0.001 (S) 0.04 (NS) < 0.001 (S)
p (pc) 0.023 (NS) 0.785 (NS) 0.007 (S)    
Family history
 Yes 1.0 (0.1–6.7)      
 No 1.6 (0.1–22.2)      
p (pc) 0.397 (NS)      
Clinical stage
 I–II 1.3 (0.1–22.2)      
 III–IV 2.1 (0.1–9.8)      
p (pc) 0.193 (NS)      
Tumor invasiveness
 Superficial 1.1 (0.1–6.7)      
 Invasive 1.9 (0.1–22.2)      
p (pc) 0.086 (NS)      
Type of therapy
 Untreated 1.1 (0.1–6.7)      
 Methotrexate 1.8 (0.1–22.2)      
 BCG 1.3 (0.1–7.9)      
p (pc) 0.464 (NS)      
  1. BCG Bacillus Calmette–Guérin, C control, N absolute number, NS not significant (p > 0.05), p Mann–Whitney U test probability, pc Corrected p, S significant (p ≤ 0.05), UBC urinary bladder cancer, UTI urinary tract infection