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Table 4 Single-nucleotide polymorphisms of TLR7 gene in females of chronic urinary tract patients and control

From: Serum level and single-nucleotide polymorphisms of toll-like receptor-7 among urinary bladder cancer Iraqi patients

TLR7 gene SNP Allele/
Genotype
UTI females
(N = 32)
Control females
(N = 24)
OR 95% CI p (pc)
N % N %
rs179018 T 48 75.0 36 75.0 1.000 (NS)
  C 16 25.0 12 25.0 1.000 (NS)
  TT 18 56.3 12 50.0 1.29 0.5–3.7 0.788 (NS)
  TC 12 37.5 12 50.0 0.60 0.2–1.7 0.419 (NS)
  CC 2 6.2 ND ND 4.02 0.2–82.5 0.510 (NS)
HWE p 1.000 0.102    
rs179019 C 44 68.8 44 91.7 0.20 0.1–0.6 0.005 (S)
  A 20 31.2 4 8.3 5.00 1.6–15.6 0.005 (S)
  CC 16 50.0 20 83.3 0.20 0.1–0.7 0.012 (NS)
  CA 12 37.5 4 16.7 3.00 0.9–10.6 0.135 (NS)
  AA 4 12.5 ND ND 7.74 0.4–142.4 0.127 (NS)
HWE p 0.471 0.656    
rs179020 G 49 76.6 44 91.7 0.30 0.1–1.0 0.043 (NS)
  A 15 23.4 4 8.3 3.37 1.1–10.8 0.043 (NS)
  GG 20 62.5 20 83.3 0.33 0.1–1.2 0.135 (NS)
  GA 9 28.1 4 16.7 1.96 0.5–7.2 0.358 (NS)
  AA 3 9.4 ND ND 5.81 0.3–111.3 0.252 (NS)
HWE p 0.221 0.656    
rs179021 T 46 71.9 36 75.0 0.85 0.4–2.0 0.830 (NS)
  G 18 28.1 12 25.0 1.17 0.5–2.7 0.830 (NS)
  TT 16 50.0 12 50.0 1.000 (NS)
  TG 14 43.8 12 50.0 0.68 0.3–2.2 0.788 (NS)
  GG 2 6.2 ND ND 4.02 0.2–82.5 0.501 (NS)
HWE p 0.642 0.103    
  1. CI Confidence interval, N absolute number, HWE Hardy–Weinberg equilibrium, ND not detected, NS not significant (p > 0.05), OR odds ratio, pc corrected p, p two-tailed Fisher’s probability, S significant (p ≤ 0.05), SNP single-nucleotide polymorphism, TLR7 Toll-like receptor 7, UTI urinary tract infection