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Table 5 Impact of TLR7 gene single-nucleotide polymorphisms on serum level of TLR-7 in males of urinary bladder cancer patients and control

From: Serum level and single-nucleotide polymorphisms of toll-like receptor-7 among urinary bladder cancer Iraqi patients

TLR7 gene SNP

Allele

Median (range); ng/ml

UBC males

Control males

rs179018

T

1.5 (0.1–22.2)

6.9 (1.9–25.1)

 

C

2.5 (0.1–7.9)

6.2 (5.0–8.2)

p (pc)

 

0.872 (NS)

0.805 (NS)

rs179019

C

1.7 (0.1–22.2)

5.1 (2.0–8.2)

 

A

1.2 (0.1–7.2)

9.6 (1.9–25.1)

p (pc)

 

0.736 (NS)

0.024 (NS)

rs179020

G

1.7 (0.1–22.2)

5.1 (2.0–8.2)

 

A

1.2 (0.1–7.2)

9.6 (1.9–25.1)

p (pc)

 

0.508 (NS)

0.024(NS)

rs179021

T

1.5 (0.1–22.2)

7.1 (1.9–25.1)

 

G

2.5 (0.1–7.9)

5.6 (2.9–8.2)

p (pc)

 

0.872 (NS)

0.347 (NS)

  1. N absolute number, NS not significant (p > 0.05), p Mann–Whitney U test, pc corrected p, SNP single-nucleotide polymorphism, TLR7 Toll-like receptor 7, UBC urinary bladder cancer