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Table 5 Impact of TLR7 gene single-nucleotide polymorphisms on serum level of TLR-7 in males of urinary bladder cancer patients and control

From: Serum level and single-nucleotide polymorphisms of toll-like receptor-7 among urinary bladder cancer Iraqi patients

TLR7 gene SNP Allele Median (range); ng/ml
UBC males Control males
rs179018 T 1.5 (0.1–22.2) 6.9 (1.9–25.1)
  C 2.5 (0.1–7.9) 6.2 (5.0–8.2)
p (pc)   0.872 (NS) 0.805 (NS)
rs179019 C 1.7 (0.1–22.2) 5.1 (2.0–8.2)
  A 1.2 (0.1–7.2) 9.6 (1.9–25.1)
p (pc)   0.736 (NS) 0.024 (NS)
rs179020 G 1.7 (0.1–22.2) 5.1 (2.0–8.2)
  A 1.2 (0.1–7.2) 9.6 (1.9–25.1)
p (pc)   0.508 (NS) 0.024(NS)
rs179021 T 1.5 (0.1–22.2) 7.1 (1.9–25.1)
  G 2.5 (0.1–7.9) 5.6 (2.9–8.2)
p (pc)   0.872 (NS) 0.347 (NS)
  1. N absolute number, NS not significant (p > 0.05), p Mann–Whitney U test, pc corrected p, SNP single-nucleotide polymorphism, TLR7 Toll-like receptor 7, UBC urinary bladder cancer