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Table 6 Impact of TLR7 gene single-nucleotide polymorphisms on serum level of TLR-7 in females of urinary tract infection patients and control

From: Serum level and single-nucleotide polymorphisms of toll-like receptor-7 among urinary bladder cancer Iraqi patients

TLR7 gene SNP

Genotype

Median (range); ng/ml

UTI females

(N = 30)

Control females

(N = 24)

rs179018

TT

5.2 (0.7–14.5)

11.0 (5.6–16.5)

 

TC

11.1 (3.3–14.0)

12.1 (7.2–17.0)

 

CC

9.8 (9.6–10.0)

ND

p (pc)

 

0.052 (NS)

0.443 (NS)

rs179019

CC

7.4 (0.7–14.0)

11.5 (5.6–17.0)

 

CA

11.5 (3.5–14.5)

12.3 (9.6–14.9)

 

AA

2.7 (0.9–3.7)

ND

p (pc)

 

0.006 (S)

0.682 (NS)

rs179020

GG

7.4 (0.7–14.1)

11.4 (5.6–17.0)

 

GA

10.8 (3.5–14.5)

12.1 (9.6–14.9)

 

AA

2.0 (0.9–3.7)

ND

p (pc)

 

0.018 (NS)

0.680 (NS)

rs179021

TT

4.4 (0.7–14.5)

11.4 (5.6–16.5)

 

TG

9.9 (3.3–14.0)

12.1 (7.2–17.0)

 

GG

9.8 (9.6–10.0)

ND

p (pc)

 

0.092 (NS)

0.653 (NS)

  1. N absolute number, ND not detected, NS not significant (p > 0.05), p Mann–Whitney U or Kruskal–Wallis H test, pc corrected p, S significant (p ≤ 0.05), SNP single-nucleotide polymorphism, TLR7 Toll-like receptor 7, UTI urinary tract infection