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Table 6 Impact of TLR7 gene single-nucleotide polymorphisms on serum level of TLR-7 in females of urinary tract infection patients and control

From: Serum level and single-nucleotide polymorphisms of toll-like receptor-7 among urinary bladder cancer Iraqi patients

TLR7 gene SNP Genotype Median (range); ng/ml
UTI females
(N = 30)
Control females
(N = 24)
rs179018 TT 5.2 (0.7–14.5) 11.0 (5.6–16.5)
  TC 11.1 (3.3–14.0) 12.1 (7.2–17.0)
  CC 9.8 (9.6–10.0) ND
p (pc)   0.052 (NS) 0.443 (NS)
rs179019 CC 7.4 (0.7–14.0) 11.5 (5.6–17.0)
  CA 11.5 (3.5–14.5) 12.3 (9.6–14.9)
  AA 2.7 (0.9–3.7) ND
p (pc)   0.006 (S) 0.682 (NS)
rs179020 GG 7.4 (0.7–14.1) 11.4 (5.6–17.0)
  GA 10.8 (3.5–14.5) 12.1 (9.6–14.9)
  AA 2.0 (0.9–3.7) ND
p (pc)   0.018 (NS) 0.680 (NS)
rs179021 TT 4.4 (0.7–14.5) 11.4 (5.6–16.5)
  TG 9.9 (3.3–14.0) 12.1 (7.2–17.0)
  GG 9.8 (9.6–10.0) ND
p (pc)   0.092 (NS) 0.653 (NS)
  1. N absolute number, ND not detected, NS not significant (p > 0.05), p Mann–Whitney U or Kruskal–Wallis H test, pc corrected p, S significant (p ≤ 0.05), SNP single-nucleotide polymorphism, TLR7 Toll-like receptor 7, UTI urinary tract infection