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Table 1 Baseline characteristics of studies included in our analysis

From: The association between angiotensin II type 1 receptor A1166C gene polymorphism and the risk of essential hypertension: a meta-analysis

Author and year Hypertension Control Country Genotyping
AA AC CC N χ2 HWE AA AC CC N χ2 HWE
Agachan et al. 2003 [18] 63 35 6 104 0.15 60 20 1 81 0.22 Turkey PCR
Ashavaid et al. 2000 [19] 91 14 0 105 0.54 159 33 0 192 1.70 India PCR-RFLP
Bautista et al. 2008 [20] 222 33 0 255 1.22 207 23 1 231 0.17 The USA PCR
Bayramoglu et al. 2015 [21] 123 19 0 142 0.73 104 4 0 108 0.04 Turkey PCR
Castellano et al. 1996 [22] 41 37 4 82 1.45 42 50 16 108 0.03 Italy PCR
Chandra et al. 2014 [9] 101 114 35 250 0.1 155 83 12 250 0.04 India PCR-RFLP
Dzida et al. 2001 [23] 131 95 24 250 1.21 96 48 6 150 0.00 Poland PCR
El-banawy et al. 2015 [24] 45 22 5 72 0.97 22 7 1 30 0.22 Egypt PCR-RFLP
Farrag et al. 2011 [25] 39 1 0 40 0.01 12 3 0 15 0.19 Egypt PCR-RFLP
Filigheddu et al. 2008 [26] 290 262 61 613 0.03 88 93 18 199 0.88 Italy PCR-RFLP
Freitas et al. 2007 [27] 60 29 1 90 1.52 58 45 12 115 0.54 Brazil PCR-RFLP
Hannila-Handelberg et al. 2010 [28] 90 49 6 145 0.04 103 62 9 174 0.01 Finland PCR
Jiang et al. 2009 [29] 201 19 0 220 0.45 212 23 0 235 0.62 China PCR
Jinmin et al. 2013 [30] 83 20 1 104 0.03 129 19 2 150 1.66 China PCR-RFLP
Kato et al. 2000 [31] 701 132 6 839 0.01 525 103 3 631 0.74 Japan PCR-RFLP
Kim et al. 2015 [32] 489 48 1 538 0.02 167 27 1 195 0.01 Korea PCR-RFLP
Kooffreh et al. 2013 [33] 605 7 0 612 0.02 606 6 0 612 0.01 Nigeria PCR-RFLP
Kretowski et al. 2007 [34] 107 131 28 266 1.71 87 79 18 184 0.00 Colorado PCR
Kurbanova and Eliseyeva 2010 [35] 122 48 2 172 1.32 41 19 0 60 2.12 Uzbekistan PCR-RFLP
Lapierre et al. 2006 [36] 24 12 1 37 0.12 22 3 0 25 0.10 Argentina PCR-RFLP
Lesage et al. 1997 [37] 35 36 3 74 2.87 64 47 9 120 0.01 France PCR
Liu et al. 2002 [38] 420 26 0 446 0.4 277 25 0 302 0.56 China PCR-RFLP
Lozinsky 2016 [39] 43 74 33 150 0.01 83 39 6 128 0.26 Ukraine PCR-RFLP
Mehri et al. 2011 [40] 26 29 8 63 0 17 24 14 55 0.85 Tunisia PCR
Morisawa et al. 2001 [41] 104 26 1 131 0.21 150 23 2 175 1.04 Japan PCR-RFLP
Nie et al. 2010 [42] 445 64 1 510 0.69 452 56 2 510 0.04 China PCR-RFLP
Onna et al. 2004 [43] 79 65 10 154 0.49 104 77 17 198 0.26 Netherlands PCR
Ono et al. 2003 [44] 1259 224 9 1492 0.08 2071 335 17 2423 0.73 Japan PCR
Parchwani et al. 2018 [45] 66 100 58 224 2.52 100 115 42 257 0.84 India PCR-RFLP
Patnaik et al. 2014 [46] 200 36 4 240 2.36 157 13 0 170 0.27 India PCR-RFLP
Saab et al. 2011 [47] 31 64 29 124 0.13 83 52 11 146 0.50 Lebanon PCR-RFLP
Schmidt et al. 1997 [48] 215 168 31 414 0.05 81 76 15 172 0.23 Germany PCR
Shahin et al. 2014 [49] 67 37 4 108 0.16 64 32 6 102 0.54 Jordan PCR-RFLP
Shamaa et al. 2016 [50] 55 21 7 83 2.54 53 7 0 60 0.23 Egypt PCR-RFLP
Soualmia et al. 2014 [51] 254 119 15 388 0.05 277 131 20 428 0.78 Tunisia PCR-RFLP
Stankovic et al. 2003 [52] 52 40 8 100 0.01 109 74 15 198 0.24 Serbia PCR
Szombathy et al. 1998 [53] 26 18 4 48 0.12 23 19 6 48 0.43 Hungary PCR-RFLP
Takami et al. 1998 [54] 261 56 4 321 0.25 172 40 3 215 0.15 Japan PCR
Tchelougou et al. 2015 [55] 195 7 0 202 0.06 197 7 0 204 0.06 Burkina Faso PCR
Thomas et al. 2000 [56] 203 28 1 232 0 152 21 1 174 0.09 Hong Kong PCR
Tiret et al. 1998 [57] 238 174 41 453 1.25 184 150 28 362 0.11 France PCR
Tong et al. 2017 [58] 278 33 1 312 0 580 42 1 623 0.07 China PCR
Tsai et al. 2003 [59] 379 29 1 409 0.31 270 16 0 286 0.24 Taiwan PCR-RFLP
van den Born et al. 2007 [60] 102 42 3 147 0.31 97 35 7 139 2.45 Netherlands PCR
Zhu et al. 2006 [61] 116 33 1 150 0.68 94 6 0 100 0.10 China PCR-RFLP
  1. HWE Hardy-Weinberg equilibrium, PCR polymerase chain reaction, RFLP restriction fragment length polymorphism