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Table 1 Genotype and allele frequency of INS -23 A>T in type 1 diabetes mellitus families

From: Association of insulin gene VNTR INS -23/Hph1 A>T (rs689) polymorphism with type 1 diabetes mellitus in Egyptian children

Group

No

INS 23 Genotype

T Allele

HWa

Wild

AA

Hetero

AT

Homo TT

AT +

TT

No

%

p

Type 1 Diabetics

91

53

58.24

36

37.36

2

4.4

38

41.758

40/182

21.97

0.143

Non-diabetic siblings

130

70

53.85

56

43.08

4

3.08

60

46.15

64/260

24.62

0.067

Parents

179

102

56.98

73

40.78

6

3.35

79

44.13

85/358

23.74

0.1

Control

96

78

81.25

17

17.71

1

1.04

18

18.75

19/192

9.895

0.945

  1. Hetero heterozygous, Homo homozygous
  2. aHardy Weinberg for genotype distribution