Egyptian Journal of Medical Human Genetics

Table 2 Concordance of INS -23/Hph1 A>T polymorphisms between type 1 diabetic children and their parents

From: Association of insulin gene VNTR INS -23/Hph1 A>T (rs689) polymorphism with type 1 diabetes mellitus in Egyptian children

Mother	Patient				Father	Patient
Mother	AA	AT	TT	Total	Father	AA	AT	TT	Total
AA	34	8	0	42	AA	25	19	0	44
AT	12	23	1	36	AT	20	15	0	35
TT	1	2	1	4	TT	1	0	1	2
Total	47	33	2	82	Total	46	34	1	81

Figures in italic = number of cases sharing INS -23/Hph1 A>T polymorphisms with their parents. Concordance rate with mothers: 58/82, Kappa value = 0.446, p = 0.000. Concordance rate with fathers: 41/81, Kappa value = 0.031, p = 0.765

Back to article page