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Table 2 Concordance of INS -23/Hph1 A>T polymorphisms between type 1 diabetic children and their parents

From: Association of insulin gene VNTR INS -23/Hph1 A>T (rs689) polymorphism with type 1 diabetes mellitus in Egyptian children

Mother Patient Father Patient
AA AT TT Total AA AT TT Total
AA 34 8 0 42 AA 25 19 0 44
AT 12 23 1 36 AT 20 15 0 35
TT 1 2 1 4 TT 1 0 1 2
Total 47 33 2 82 Total 46 34 1 81
  1. Figures in italic = number of cases sharing INS -23/Hph1 A>T polymorphisms with their parents. Concordance rate with mothers: 58/82, Kappa value = 0.446, p = 0.000. Concordance rate with fathers: 41/81, Kappa value = 0.031, p = 0.765