Parameters | PAI-1 genotypes in DM without VCs | P value | ||
---|---|---|---|---|
5G/5G (n = 29) | 4G/5G (n = 48) | 4G/4G (n = 40) | ||
Age (years) | 48.0 (12.0) | 47.0 (10.5) | 48.0 (10.0) | 0.890 NS, 1 |
Gender [n (%)] | Â | Â | Â | 0.498 NS, 2 |
Male | 22 (75.9) | 36 (75.0) | 26 (65.0) | Â |
Female | 7 (24.1) | 12 (25.0) | 14 (35.0) | Â |
Smoking [n (%)] | Â | Â | Â | 0.002 HS, 2 |
No | 25 (86.2) | 28 (58.3) | 35 (87.5) | Â |
Yes | 4 (13.8) a | 20 (41.7) b | 5 (12.5) a | Â |
Dyslipidemia [n (%)] | Â | Â | Â | 0.017 HS, 3 |
Absent | 4 (13.8) | 1 (2.1) | 0 (0.0) | Â |
Present | 25 (86.2) a | 47 (97.9) a, b | 40 (100.0) b | Â |
Hypertension [n (%)] |  |  |  | < 0.001 HS, 3 |
Absent | 12 (41.4) | 2 (4.2) | 4(10.0) | Â |
Present | 17 (58.6) a | 46 (95.8) b | 36 (90.0) b | Â |
Duration of DM (years) | 3.20 (1.65) | 3.80 (2.10) | 3.6 (2.03) | 0.221 NS |
PAI-1 | 27.0 (7.50)a | 55.0 (10.75)b | 41.5 (9.0)c | < 0.001 HS, 1 |
TAFI | 31.0 (13.50)a | 78.5 (24.0)b | 50.0 (21.50)c | < 0.001 HS, 1 |
d-dimer (mg/dl) | 0.60 (0.25)a | 2.80 (1.25)b | 1.25 (1.08)c | < 0.001 HS, 1 |
BMI (Kg/m3) | 27.4 (2.80)a | 31.45 (6.38)b | 27.80 (3.73)a | < 0.001 HS, 1 |
SBP (mmHg) | 120.0 (8.0)a | 155.0 (40.0)b | 120.0 (29.5)c | < 0.001 HS, 1 |
DBP (mmHg) | 80.0 (10.5)a | 95.0 (21.0)b | 86.0 (11.5)a | < 0.001 HS, 1 |
FBS (mg/dl) | 117.0 (23.0)a | 132.0 (23.0)b | 124.50 (28.25)a, b | < 0.001 HS, 1 |
2Hr BS (mg/dl) | 132.0 (21.50)a | 155.5 (33.25)b | 140.0 (32.75)a, b | 0.003 HS |
HbA1c (%) | 6.7 (0.75)a | 7.7 (2.55)b | 7.15 (1.15)a, b | < 0.001 HS, 1 |
T.C (mg/dl) | 186.0 (17.5)a | 200.0 (23.25)b | 194.5 (25.25)b | 0.002 HS, 1 |
Triglycerides (mg/dl) | 152.0 (46.5)a | 156.0 (22.5)a, b | 165.0 (37.25)b | 0.013 S, 1 |
LDL (mg/dl) (mean ± SD) | 118.91 ± 12.49a | 130.78 ± 18.46b | 128.80 ± 17.71b | 0.011 S, 4 |
HDL (mg/dl) | 34.0 (8.0) | 32.0 (8.5) | 33.0 (5.75) | 0.528 NS, 1 |