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Table 1 Demographic data of young mothers with DS in comparison to control mothers

From: The demographic data and the high frequency of chromosome/chromatid breaks as biomarkers for genome integrity have a role in predicting the susceptibility to have Down syndrome in a cohort of Egyptian young-aged mothers

Variable DS mothers Control mothers OR (95% CI) P value
Consanguinity Present 23 (46%) 10 (20%) 3.40 (1.4–8.20) 0.006*
Absent 27 (54%) 40 (80%)
Socioeconomic status High 19 (38%) 35 (70%) 3.80 (1.65–8.74) 0.001*
Low 31 (62%) 15 (30%)
Residency area Rural 30 (60%) 18 (36%) 2.66 (1.18–5.98) 0.017*
Urban 20 (40%) 32 (64%)
  1. *Statistically significant at P ≤ 0.05