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Table 2 Association between chromosome/chromatid breaks and young mothers with DS in comparison to control mothers

From: The demographic data and the high frequency of chromosome/chromatid breaks as biomarkers for genome integrity have a role in predicting the susceptibility to have Down syndrome in a cohort of Egyptian young-aged mothers

Studied group Chromosome/chromatid breaks Total χ 2 P value
Present Absent
Young mothers with DS 38 (76%) 12 (24%) 50 (100%) 19.485* < 0.001*
Control mothers 16 (32%) 34 (68%) 50 (100%)
  1. χ2 chi-square test
  2. *Statistically significant at P ≤ 0.05