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Egyptian Journal of Medical Human Genetics

Table 2 Association between chromosome/chromatid breaks and young mothers with DS in comparison to control mothers

From: The demographic data and the high frequency of chromosome/chromatid breaks as biomarkers for genome integrity have a role in predicting the susceptibility to have Down syndrome in a cohort of Egyptian young-aged mothers

Studied group

Chromosome/chromatid breaks

Total

χ 2

P value

Present

Absent

Young mothers with DS

38 (76%)

12 (24%)

50 (100%)

19.485*

< 0.001*

Control mothers

16 (32%)

34 (68%)

50 (100%)

  1. χ2 chi-square test
  2. *Statistically significant at P ≤ 0.05
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