The demographic data and the high frequency of chromosome/chromatid breaks as biomarkers for genome integrity have a role in predicting the susceptibility to have Down syndrome in a cohort of Egyptian young-aged mothers

Egyptian Journal of Medical Human Genetics

Table 4 The association of socioeconomic status and residency area with chromosome/chromatid breaks in young mothers with history of a DS child

Studied variable		Chromosome/chromatid breaks		OR (95% CI)	P value
Studied variable		Present (no. 38)	Absent (no. 12)	OR (95% CI)	P value
Socioeconomic status	High	12 (31.6%)	7 (58.3%)	0.330 (0.087–1.254)	0.104
Socioeconomic status	Low	26 (68.4%)	5 (41.7%)	3.033 (0.797–11.539)	0.104
Residency area	Rural	22 (57.9%)	8 (66.7%)	0.688 (0.176–2.684)	0.589
Residency area	Urban	16 (42.1%)	4 (33.3%)	1.454 (0.372–5.679)	0.589