Adiponectin and human eating behaviour: a Mendelian randomization study

Egyptian Journal of Medical Human Genetics

Table 1 Characteristics of SNPs selected for Mendelian randomization

ADIPOQ SNP	Chr	Position*	EA	NEA	EAF^†	C1	S6
rs864265	3	186836503	G	T	0.14		✓
rs16861205	3	186843845	G	A	0.85	✓	✓
rs182052	3	186842993	G	A	0.61		✓
rs17366568	3	186852664	G	A	0.93		✓
rs3821799	3	186853697	T	C	0.54		✓
rs3774261	3	186853770	A	G	0.50		✓

Chr chromosome, EA effect allele, EAF effect allele frequency, NEA non-effect allele, S6 six SNPs used in MR analyses (all but one SNP were selected on basis of reaching genome-wide significant levels in association with adiponectin, P < 5 × 10⁻⁸ in ADIPOGen consortium); and C1 one SNP had a P < 2.3 × 10⁻⁷ in association with adiponectin in the ADIPOGen consortium
*Genome Reference Consortium Human Build 38
^†1000 genomes