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Table 3 Estimates of standardized mean difference, standard error, P values (and 95% confidence interval [CI]) of three eating behaviour factors per 1 U increase in genetically instrumented log adiponectin levels from various Mendelian randomization methods

From: Adiponectin and human eating behaviour: a Mendelian randomization study

MR method EB factor restraint EB factor disinhibition EB factor hunger
β SE 95% CI P β SE 95% CI P β SE 95% CI P
IVW 0.17 1.03 − 1.85, 2.18 0.87 3.05 1.00 1.10, 5.00 0.002 1.63 1.22 − 0.75, 4.01 0.18
Weighted median 0.98 1.15 − 1.28, 3.24 0.40 2.66 1.11 0.48, 4.84 0.02 1.23 1.09 − 0.90, 3.36 0.26
Weighted modal 1.07 1.12 − 1.12, 3.26 0.34 2.63 1.07 0.54, 4.73 0.01 1.12 1.03 − 0.90, 3.14 0.28
MR Egger 3.85 2.23 − 0.52, 8.21 0.08 − 0.32 2.23 − 4.69, 4.04 0.88 − 1.53 2.74 − 6.89, 3.83 0.58
Constant − 0.25 0.14 − 0.53, 0.02 0.07 0.23 0.14 − 0.04, 0.51 0.10 0.22 0.17 − 0.12, 0.55 0.20
  1. CI confidence interval, U unit, EB eating behaviour, IVW inverse-variance weighted regression method, β beta coefficient, SE standard error
  2. MR-Egger intercept