Fig. 3
From: Flavanones from Sorghum bicolor selectively inhibit COX-2: in-silico and in-vivo validation
a Interactions of celecoxib (orange) with key residues at the catalytic site of COX-2, the dotted red lines represent the hydrophobic interactions while the blue lines represent hydrogen bonds interactions. b Interactions of celecoxib (orange) with key residues at the catalytic site of COX-1; the dotted red lines represent hydrophobic interactions while the blue lines represent hydrogen bonds interactions. c Interactions of eriodicytol (orange) with key residues at the catalytic site of COX-2; the dotted red lines represent hydrophobic interactions while the blue lines represent hydrogen bonds interactions. d Interactions of eriodicytol (orange) with key residues at the catalytic site of COX-1; the dotted red lines represent hydrophobic interactions, the blue lines represent hydrogen bonds interactions and the dotted green lines represent Pi-stacking