Table 1 Docking scores of the lead, other flavanones (Hesperetin and Naringenin), and the standard drugs (Celecoxib, ibuprofen, Indomethacin)
From: Flavanones from Sorghum bicolor selectively inhibit COX-2: in-silico and in-vivo validation
Compounds | Docking scores COX-1 | Docking scores COX-2 |
|---|---|---|
Celecoxib | − 10.3 | − 11.2 |
Eriodictyol | − 7.8 | − 8.4 |
Hesperetin | − 7.3 | − 8.5 |
Ibuprofen | − 7.0 | − 7.4 |
Indomethacin | − 8.9 | − 7.2 |
Naringenin | − 6.7 | − 7.8 |