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Table 1 Distribution of the retrieved SNPs of the bovine LEP gene. The bolded SNPs were the nonsynonymous SNPs that are selected for the present comprehensive study

From: D76V, L161R, and C117S are the most pathogenic amino acid substitutions with several dangerous consequences on leptin structure, function, and stability

No.

Type of SNP

No. of SNPs

1

Start retained variant

1

2

5′ UTR variants

14

3

Synonymous variants

76

4

Missense (non-synonymous)variants

90

5

Frameshift variants

5

6

Inframe deletion

1

7

Splice acceptor variant

2

8

Splice donor variant

1

9

Stop gained

3

10

Intronic variants

2939

11

Splice region variants

15

12

3′ UTR variants

734

Total

 

3881