Egyptian Journal of Medical Human Genetics

Table 4 TM-align predictions for the most three deleterious nsSNPs in leptin

From: D76V, L161R, and C117S are the most pathogenic amino acid substitutions with several dangerous consequences on leptin structure, function, and stability

NsSNP ID	Amino acid change	Aligned length	TM-score	RMSD (Å)
rs1332916395	D76V	153	0.82942	0.948
rs1051206328	C117S	166	0.93578	0.940
rs771956117	L161R	152	0.83738	0.967

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