Table 3 Association of studied SNPs with lung cancer under different genetic models of inheritance
SNP | Dominant | Co-dominant | Recessive | Over dominant |
|---|---|---|---|---|
rs1051730 | ||||
Genotype | (A/G + A/A vs. G/G) | (A/G vs. G/G) or (A/G vs. AA) | (A/G + G/G vs. A/A) | A/G vs. G/G +A/A |
OR (95%CI) | 1.2(0.4-3.2) | 0.8 (0.3–2.4)/1.3 (0.3–5.1) | 0.7 (0.2–2.7) | 1.0 (0.4–2.5) |
p value | 0.7 | 0.8/0.7 | 0.6 | 0.9 |
rs25487 | ||||
Genotype | (A/C + C/C vs. A/A) | (A/C vs. A/A or C/C) | A/C + A/A vs. C/C | A/C vs. A/A + C/C |
OR (95%CI) | 1.6 (0.5–4.4) | 0.7 (0.2–2.0) | 1.6 (0.5–4.4) | 0.8 (0.2–2.2) |
p value | 0.3 | 0.5 | 0.3 | 0.6 |
rs735482 | ||||
Genotype | (A/G + GG vs. AA) | (A/G vs. A/A or G/G) | A/G + A/A vs. G/G | A/G vs. A/A + G/G |
OR (95%CI) | 1.8 (0.7–4.6) | 2.0 (0.7–5.3)/1.3 (0.2–6.7) | 1.0 (0.2–4.8) | 0.5 (0.2–1.3) |
p value | 0.1 | 0.1/0.7 | 0.9 | 0.1 |