Table 7 Association between TERT gene amplification and clinicopathological and cytogenetic characteristics of all patients

Age (mean ± SD)

58.6 ± 11.7

61.5 ± 11.7

0.4

Sex

0.52

 Male

19

11

 Female

8

7

Presentation at the time of diagnosis

0.0008

 DNV

26

10

 Relapse

1

8

Hepatomegaly

3

7

0.08

Splenomegaly

4

12

0.004

Lymphadenopathy

12

13

0.3

WBC count (mean ± SD) (× 10³/μl)

11.03 ± 7.6

9.61 ± 9.8

0.59

Hb level (mean ± SD) (g/dl)

11.39 ± 2.68

10.69 ± 2.3

0.36

Platelet count (mean ± SD) (× 10³/μl)

147.2 ± 80.4

124 ± 48.5

0.26

Chromosomal aberrations by conventional karyotype

6

9

0.052

13q14.3 deletion

3

2

0.2

14q32 rearrangement

4

2

1

P53(17p13.1) deletion

3

6

0.011

Prognosis

0.021

 Good (I)

16

4

 Intermediate (II)

4

2

 Bad (III)

7

12