Table 2 Diagnostic performance of methylation to differentiate early and late tumor stages
From: Aberrant methylation of yes-associated protein (YAP1) as a potential biomarker in breast cancer
| Ā | Tumor stage | Sensitivity | Specificity | PPV | NPV | Accuracy | |||
|---|---|---|---|---|---|---|---|---|---|
Early (nā=ā18) | Late (nā=ā32) | ||||||||
n | % | n | % | ||||||
Methylation | |||||||||
āUnmethylated | 15 | 83.3 | 1 | 3.1 | 96.88 | 83.33 | 91.18 | 93.75 | 92.0 |
āMethylated | 3 | 16.7 | 31 | 96.9 | |||||
Ļ2 (p) | 34.059*(<ā0.001*) | Ā | Ā | Ā | Ā | Ā | |||