Table 6 Relation between TNF-α -308 G>A and IL-10 -1082 A>G alleles/genotype with risk factors in group III

 Male

9 (32.1%)

9(75%)

χ²=6.23^*

(0.013^*)

2 (20%)

5 (62.5%)

2(100%)

χ² =5.96^*

(0.049^*)

11(36.7%)

7 (70%)

χ² =3.37

(0.07)

4 (33.3%)

3 (50%)

2(100%)

χ² =3.17

(0.21)

 Female

19(67.9%)

3(25%)

8 (80%)

3 (37.5%)

0 (0%)

19(63.3%)

3 (30%)

8 (66.7%)

3 (50%)

0 (0%)

 median(range)

8(4 – 11)

8(5.5-9)

U =112.0

(0.18)

8(7 -11)

7(5.5-9)

8.5(8-9)

H =3.02

(0.22)

8(4 –11)

6.8(4-8)

U =76.0

(0.17)

8.1(5.5-11)

4.8 (4-5.5)

6.5 (6-7)

H =12.7^*

(0.002^*)

 mean± SD.

7.4 ± 2.2

8 ± 1.6

7.6 ± 2.4

5.5 ± 1.8

8.5 ± 0.7

7.6 ± 2.04

6.4 ± 2.0

8.0^ab¥± 1.8

4.7^b¥ ± 0.9

6.5^a¥± 0.7

 median(range)

96(75-126)

92(88-115)

U=114.0

(0.59)

96(75 –126)

115 (92 –115)

88.3(87.5-89)

H =1.52

(0.47)

106(84-126)

85.5(75-115)

U =60.0^*

(0.049^*)

104(84–126)

106(96–115)

75.5(73–78)

H =5.19

(0.075)

 mean ±SD.

101.5±18.5

99.6± 13.3

99.8 ± 20.5

107.3 ± 12

88.3 ± 1.1

104.1 ± 16

90.3 ± 17.8

104 ± 17

105.5± 11

75.5± 3.5

 median(range)

72(32-105)

72(46-94)

U=122.0

(0.79)

48(44-52)

94(72-94)

66(32-105)

H =5.18

(0.075)

77.5(46-105)

42.5 (32–94)

U =52.0^*

(0.02^*)

78(46– 105)

74(53– 94)

33(31-35)

H =5.19

(0.075)

 mean± SD.

72.2 ± 24.3

70.4 ± 23

48 ± 5.5

86.7 ± 11.4

67.8 ± 26.3

77.1± 19.8

52.8 ± 27.1

77.7 ± 20

73.5 ± 24

33± 2.8

RF

(n = 15)

(n = 3)

(n = 6)

(n = 3)

(n = 0)

(n = 13)

(n = 5)

(n = 6)

(n = 0)

(n = 3)

 median(range)

112(64-128)

64(64-64)

t =2.47^*

(0.027^*)

128(80-128)

64(64-64)

-

128 (80-128)

64(64-64)

t =5.86

(<0.001)

128(80-128)

–

64(64-64)

t =3.83^*

(0.009^*)

 mean± SD.

128 ± 27.7

64 ± 0.0

120± 19.6

64 ± 0.0

-

120±18.7

64±0.0

120±19.6

–

64±0.0

AIHA

8

4

χ²=0.28

(0.59)

2

4

-

χ²=4.80

(0.09)

10

2

χ²=0.32

(0.57)

4

2

-

χ²=1.50

(0.47)