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Table 2 Baseline characteristics of studies concerning CaSR A986S gene polymorphism in patients with urolithiasis included in the meta-analysis

From: Association between calcium-sensing receptor (CaSR) R990G, CaSR A986S, and CaSR Q1011E gene polymorphisms and the risk of urolithiasis: a meta-analysis

Author and year

Case

Control

Ethnicity

Type of stone

Genotyping

X2 HWE

NOS [S/C/E]

AA

AS

SS

N

AA

AS

SS

N

Corbetta et al. 2006 [39]

58

28

8

94

91

42

4

137

Caucasian

Calcium oxalate

PCR

0.10

6[3/1/2]

Ding et al. 2017 [26]

589

25

1

615

303

12

0

315

Asian

Calcium oxalate

PCR

0.12

6[3/1/2]

Guha et al. 2015 [38]

116

82

2

200

162

37

1

200

Asian

Calcium oxalate

PCR

0.52

7[3/2/2]

Hamilton et al. 2009 [30]

110

33

14

157

372

91

6

469

Caucasian

Calcium oxalate

PCR-RFLP

0.03

7[3/2/2]

Han et al. 2013 [31]

64

5

1

70

88

6

0

94

Asian

Calcium oxalate

PCR

0.10

6[3/1/2]

Kim et al. 2011 [40]

415

18

0

433

191

6

0

197

Asian

Calcium oxalate and citrate

PCR-RFLP

0.05

7[3/2/2]

Li et al. 2018 [32]

561

62

1

624

435

35

0

470

Asian

Calcium oxalate

PCR

0.70

8[4/2/2]

Peretokina et al. 2015 [33]

78

26

6

110

48

25

4

77

Caucasian

Calcium phosphate

PCR

0.10

6[3/1/2]

Shakhssalim et al. 2010 [27]

71

26

2

99

93

14

0

107

Asian

Calcium oxalate

PCR

0.52

7[4/1/2]

  1. CaSR calcium-sensing receptor, PCR polymerase chain reaction, PCR-RFLP PCR–restriction fragment length polymorphism, HWE Hardy-Weinberg equilibrium, NOS Newcastle-Ottawa Scale, S selection, C comparability, E exposure