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Table 1 Characterization of MYH7 missense variants along with exon location, allele frequencies in Iranian ethnic groups and the international published references

From: Prediction and in silico validation of MYH7 gene missense variants in the Iranian population: a bioinformatics analysis based on Iranome database

Variant

dbSNP

Exon

Allele (n)

Allele frequency

Ethnicity

p.Ala26Val 14:23902865 G/A

rs186964570

3

2

0.00125

Turkmen

p.Pro211Leu 14:23900977 G/A

rs727503277

7

1

0.000625

Persian

p.Arg787His 14:23894554 C/T

rs376754645

21

1

0.000625

Persian Gulf Islander

p.Val964Leu 14:23893148 C/G

rs45496496

23

2

0.00125

Turkmen/Persian

p.Ala1191Thr 14:23889209 C/T

rs774151903

27

1

0.0006775

Lur

p.Arg1129Ser 14:23889393 C/G

27

1

0.0006297

Persian

p.Asn1257Ser 14:23888775 T/C

rs574005462

28

2

0.00125

Baloch/Persian Gulf Islander

p.Arg1277Gln 14:23888715 C/T

rs397516195

28

4

0.0025

Baloch/Persian

p.Ser1366Leu 14:23887491 G/A

rs767000995

30

1

0.0006258

Azeri

p.Ser1491Cys 14:23886409 G/C

rs3729823

32

22

0.01375

Various

p.Phe1498Tyr 14:23886388 A/T

32

1

0.000625

Arab

p.Ser1596Leu 14:23885379 G/A

rs774540446

34

1

0.000625

Persian

p.Arg1588His 14:23885403 C/T

34

1

0.000625

Baloch

p.Ala1603Thr 14:23885359 C/T

rs730880809

34

1

0.000625

Azeri

p.Asn1623Ser 14:23885298 T/C

34

1

0.000625

lur

p.Arg1662His 14:23885010 C/T

rs370328209

35

1

0.000625

Azeri

p.Asn1824Asp 14:23884293 T/C

rs769112519

37

1

0.000625

Persian

p.Asn1824Ser 14:23884292 T/C

rs760218400

37

1

0.000625

Persian