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Table 2 The association between three common XPC polymorphisms and the risk of age-related macular degeneration

From: Lack of association between three common genetic variations of XPC and susceptibility to age-related macular degeneration, a preliminary study

Polymorphisms/genetic modelsControlsCasesOR95% CIPOR*95% CIP
PAT        
Additive model        
 -/-33311.01.0
 -/+57601.120.61–2.060.7141.110.58–2.110.746
 +/+28291.100.54–2.250.7890.920.44–1.950.846
Dominant model        
 -/-33311.01.0
 -/+ and +/+85891.110.62–1.970.7111.040.57–1.910.881
Recessive model        
 -/- and -/+90911.01.0
 +/+28291.020.56–1.850.9370.860.46–1.610.653
Minor allele frequency0.47880.49171.050.73–1.500.779   
Ala499Val        
Additive model        
 Ala/Ala72731.01.0-
 Ala/Val41390.930.54–1.620.8191.020.57–1.810.947
 Val/Val581.570.49–5.050.4421.480.45–4.920.515
Dominant model        
 Ala/Ala72731.01.0
 Ala/Val + Val/Val46471.010.59-1.690.9771.070.62–1.860.791
Recessive model        
 Ala + Ala/Val1131121.01.0
 Val/Val581.610.51–5.080.4131.470.45–4.800.517
Minor allele frequency0.21610.22911.070.70–1.660.732   
Lys939Gln        
Additive model        
 Lys/Lys31301.01.0
 Lys/Gln58611.080.58–2.010.7921.040.54–1.990.899
 Gln/Gln29291.030.50–2.120.9290.840.39–1.780.656
Dominant model        
 Lys/Lys31301.01.0
 Lys/Gln + Gln/Gln87901.060.59–1.910.8220.970.52–1.790.927
Recessive model        
 Lys/Lys + Lys/Gln89911.01.0
 Gln/Gln29290.980.54–1.760.9410.820.44–1.520.528
Minor allele frequency0.49150.49581.010.71–1.450.925   
  1. *Adjusted ORs for age of participants