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Table 4 Frequency of different genotypes and allele of ACE ID polymorphism in patients with and without cardiac autonomic neuropathy

From: Angiotensin-converting enzyme insertion/deletion (I/D) gene polymorphism in Iraqi type 2 diabetic patients: association with the risk of cardiac autonomic neuropathy

ACE ID polymorphism

Diabetic patients n = 117

p value

OR (95% CI)

With CAN n = 55

Without CAN n = 62

Genotypes

 II

3 (5.45%)

7 (11.29%)

0.196

1.0 ref.

 ID

14 (25.45%)

22 (35.48%)

0.608

1.5 (0.33–6.71)

 DD

38 (69.1%)

33 (53.23%)

0.176

2.7 (0.64–11.24)

HWE

0.284

0.274

  

Alleles

 I

20 (18.18%)

36 (29.03%)

0.054

1.0 ref.

 D

90 (81.82%)

88 (70.97%)

 

1.84 (0.99–3.42)

  1. CAN cardiac autonomic neuropathy, HWE Hardy-Weinberg equilibrium (using logistic regression)