The associations among RARRES2 rs17173608 gene polymorphism, serum chemerin, and non-traditional lipid profile in patients with metabolic syndrome

Egyptian Journal of Medical Human Genetics

Table 4 Genotyping and allelic frequencies distribution of RARRES2 rs17173608 gene polymorphism between controls (non-MetS) and metabolic syndrome (MetS) group, and between T2DM and non-diabetics patients

Genotype		Non-MetS group (n = 68) (%)	MetS group (n = 100) (%)	OR	95% CI	p value	Non-diabetics (84)	T2DM (n = 84)	Odds ratio	95% CI	p value
TT*		38 (55.88%)	36 (36.0%)	Ref	Ref	Ref	28 (33.33%)	51 (60.71%)	Ref	Ref	Ref
TG		22 (32.36%)	32 (32.0%)	1.5354	0.75 to 3.12	0.2358	24 (28.57%)	25 (29.76%)	0.58	0.28 to 1.18	0.131
GG		8 (11.8%)	32 (32.0%)	4.2222	1.7185 to 10.374	0.0017	32 (38.1%)	8 (9.52%)	0.137	0.055 to 0.338	0.0001
Recessive	TT + TG	60 (88.23%)	68 (68%)	3.5294	1.5101 to 8.249	0.00364	52 (61.9%)	76 (90.47%)	0.171	.0.0730 to 0.4007	0.0001
Recessive	GG	8 (11.76%)	32 (32%)	3.5294	1.5101 to 8.249	0.00364	32 (38.1%)	8 (9.52%)	0.171	.0.0730 to 0.4007	0.0001
Dominant	TT	38 (55.88%)	36 (36%)	0.4441	0.2367 to 0.833	0.00141	28 (33.33%)	51 (60.71%)	0.323	0.172 to 0.608	0.0005
Dominant	TG + GG	30	64 (64%)	0.4441	0.2367 to 0.833	0.00141	56 (66.67%)	33 (39.3%)	0.323	0.172 to 0.608	0.0005
Additive	TT	38 (55.88%)	36 (36%)	4.2222	1.7185 to 10.374	0.0017	28 (33.33%)	51 (60.71%)	0.137	0.055 to 0.338	0.0001
Additive	GG	8 (11.76%)	32 (32%)	4.2222	1.7185 to 10.374	0.0017	32 (38.1%)	8 (9.52%)	0.137	0.055 to 0.338	0.0001
Alleles	T*	98 (72.06)	104 (52%)	2.3806	1.4937 to 3.7941	0.0003	80 (47.62%)	127 (7%5.6)	0.293	0.1845 to 0.467	0.000
Alleles	G	38 (27.94)	96 (48%)	2.3806	1.4937 to 3.7941	0.0003	88 (52.38%)	41 (24.4%)	0.293	0.1845 to 0.467	0.000

Data are represented as numbers and percentages. p < 0.05 is considered to be significant
Numbers in bold indicated significant values
OR odds ratio, CI confidence interval