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Egyptian Journal of Medical Human Genetics

Table 4 TNF-α and TGF-β assessment in the different studied rats’ groups

From: Role of mesenchymal stem cells and their culture medium in alleviating kidney injury in rats diabetic nephropathy

Studied groups

Inflammatory markers

TGF-β1 (pg/mg protein)

TNF-α (pg/mg protein)

Control (n = 15)

80.63 ± 10.42

18.09 ± 0.86

DN (n = 15)

206.17 ± 22.30a

43.14 ± 1.13a

Fibroblast (n = 15)

210.12 ± 11.32a

40.22 ± 1.33a

AD-MSC (n = 15)

101.05 ± 6.04b,c

25.40 ± 0.29b,c

CM (n = 15)

98.15 ± 5.24b,c

23.92 ± 0.17b,c

F

591.81

2132.72

P

< 0.001

< 0.001

  1. One-way ANOVA, post hoc tests, P > 0.05 no significant differences, P < 0.05 significant differences, and P < 0.001 highly significant differences
  2. TNF-α tumor necrosis factor alpha, TGF-β transforming growth factor beta 1
  3. aSignificant difference vs control group
  4. bSignificant difference vs DN group
  5. cSignificant difference vs fibroblast group
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