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Table 4 TNF-α and TGF-β assessment in the different studied rats’ groups

From: Role of mesenchymal stem cells and their culture medium in alleviating kidney injury in rats diabetic nephropathy

Studied groupsInflammatory markers
TGF-β1 (pg/mg protein)TNF-α (pg/mg protein)
Control (n = 15)80.63 ± 10.4218.09 ± 0.86
DN (n = 15)206.17 ± 22.30a43.14 ± 1.13a
Fibroblast (n = 15)210.12 ± 11.32a40.22 ± 1.33a
AD-MSC (n = 15)101.05 ± 6.04b,c25.40 ± 0.29b,c
CM (n = 15)98.15 ± 5.24b,c23.92 ± 0.17b,c
F591.812132.72
P< 0.001< 0.001
  1. One-way ANOVA, post hoc tests, P > 0.05 no significant differences, P < 0.05 significant differences, and P < 0.001 highly significant differences
  2. TNF-α tumor necrosis factor alpha, TGF-β transforming growth factor beta 1
  3. aSignificant difference vs control group
  4. bSignificant difference vs DN group
  5. cSignificant difference vs fibroblast group