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Table 2 Comparison between the two studied groups according to DNMT3A expression and NO level before and after treatment

From: Prognostic significance of DNMT3a gene expression and reactive nitrogen species in newly diagnosed Egyptian de novo adult acute myeloid leukemia patients

  Cases Control
(n = 10)
Before
(n = 45)
After
(n = 26)
DNMT3A expression
 Min.–Max. 18.60–83.60 2.96–71.20 0.54–1.72
 Mean ± SD 46.64 ± 19.90 24.88 ± 21.39 0.94 ± 0.36
 Median 46.50 17.05 0.98
Significance between groups p1 < 0.001*, p2 < 0.001*, p3 < 0.001*
NO level    
 Min.–Max. 0.53–60.90 0.0–27.50 0.0–22.11
 Mean ± SD 16.06 ± 13.90 8.81 ± 7.43 7.83 ± 7.35
 Median 12.0 6.20 5.80
Significance between groups p1 = 0.008*, p2 = 0.035*, p3 = 0.538
  1. p1: P value for Wilcoxon signed-ranks test for comparing between before and after
  2. p2: P value for Mann-Whitney test for comparing between before and control
  3. p3: P value for Mann-Whitney test for comparing between after and control