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Table 5 Comparison between levels of DNMT3A gene expression and NO level before and after treatment

From: Prognostic significance of DNMT3a gene expression and reactive nitrogen species in newly diagnosed Egyptian de novo adult acute myeloid leukemia patients

   Level of expression U P
Low expression High expression
DNMT3A expression Before (n= 22) (n= 23)   
 Min.–Max. 18.60–42.30 46.50–83.60 0.000* <0.001*
 Mean ± SD 29.26 ± 8.26 63.27 ± 11.65
 Median 27.80 61.20
After (n= 13) (n= 13)   
 Min.–Max. 2.96–23.40 5.69–71.20 17.00* 0.001*
 Mean ± SD 10.58 ± 6.68 39.18 ± 21.57
 Median 10.20 43.60
NO Level Before (n= 22) (n= 23)   
 Min.–Max. 0.53–46.90 3.20–60.90 207.00 0.296
 Mean ± SD 14.14 ± 12.44 17.90 ± 15.21
 Median 9.55 13.40
After (n= 13) (n= 13)   
 Min.–Max. 0.0–26.60 0.0–27.50 83.50 0.959
 Mean ± SD 8.47 ± 6.81 9.15 ± 8.26
 Median 6.20 7.50
  1. U, p: U and P values for Mann-Whitney test
  2. *Signifies statistical significance