Egyptian Journal of Medical Human Genetics

Table 6 Comparison of DNMT3A expression and NO level before and after treatment in relation to DNMT3A mutational status

From: Prognostic significance of DNMT3a gene expression and reactive nitrogen species in newly diagnosed Egyptian de novo adult acute myeloid leukemia patients

		DNMT3A mutation		U	P
		Mutated	Wild-type	U	P
DNMT3A expression	Before	(n= 12)	(n= 33)
	Min.–Max.	19.70–83.60	18.60–79.40	125.50	0.063
	Mean ± SD	56.43 ± 21.15	43.09 ± 18.49
	Median	54.85	39.60
	After	(n= 6)	(n= 20)
	Min.–Max.	2.96–62.10	3.02–71.20	48.50	0.484
	Mean ± SD	20.16 ± 21.70	26.29 ± 21.65
	Median	14.05	18.25
NO level	Before	(n= 12)	(n= 33)
	Min.–Max.	0.53–30.20	2.70–60.90	152.0	0.238
	Mean ± SD	11.49 ± 9.12	17.72 ± 15.04
	Median	10.12	14.70
	After	(n= 6)	(n= 20)
	Min.–Max.	0.0–13.10	0.0–27.50	50.0	0.543
	Mean ± SD	6.25 ± 4.49	9.58 ± 8.03
	Median	6.10	6.46

U, p: U and P values for Mann-Whitney test

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