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Table 6 Comparison of DNMT3A expression and NO level before and after treatment in relation to DNMT3A mutational status

From: Prognostic significance of DNMT3a gene expression and reactive nitrogen species in newly diagnosed Egyptian de novo adult acute myeloid leukemia patients

   DNMT3A mutation U P
  Mutated Wild-type
DNMT3A expression Before (n= 12) (n= 33)   
 Min.–Max. 19.70–83.60 18.60–79.40 125.50 0.063
 Mean ± SD 56.43 ± 21.15 43.09 ± 18.49
 Median 54.85 39.60
After (n= 6) (n= 20)   
 Min.–Max. 2.96–62.10 3.02–71.20 48.50 0.484
 Mean ± SD 20.16 ± 21.70 26.29 ± 21.65
 Median 14.05 18.25
NO level Before (n= 12) (n= 33)   
 Min.–Max. 0.53–30.20 2.70–60.90 152.0 0.238
 Mean ± SD 11.49 ± 9.12 17.72 ± 15.04
 Median 10.12 14.70
After (n= 6) (n= 20)   
 Min.–Max. 0.0–13.10 0.0–27.50 50.0 0.543
 Mean ± SD 6.25 ± 4.49 9.58 ± 8.03
 Median 6.10 6.46
  1. U, p: U and P values for Mann-Whitney test