SHOX2 gene methylation in Egyptians having lung cancer

Egyptian Journal of Medical Human Genetics

Table 8 Comparison between controls and cases regarding the percentage of SHOX2 gene methylation

Methylation percentage	Controls (n = 20)	Cases (n = 60)	Test of sig.	p
*Un-methylatedSHOX2(%)*
Min–Max	92.14–96.48	22.84–96.10	t = 4.324^*	<0.001^*
Mean ± S.D.	94.38 ± 1.80	78.82 ± 18.12
Median	94.92	84.34
*MethylatedSHOX2(%)*
Min–Max	3.52–7.86	3.90–77.16	U = 23.50^*	<0.001^*
Mean ± S.D.	5.62 ± 1.80	21.18 ± 18.12
Median	5.08	15.67

U: Mann Whitney test, t: Student t test, p: p value for comparing between the two groups
*Statistically significant at p ≤ 0.05