From: Spinal muscular atrophy in Venezuela: quantitative analysis of SMN1 and SMN2 genes
Gene | Estimated number of copies | Ranges of values of 2−ΔΔCT | SD | Number of individuals (n = 49) | Frequency (%) |
---|---|---|---|---|---|
SMN1 | 1 | 0.35 | - | 1 | 2.0 |
1 or 2 (*) | 0.66–0.72 | - | 6 | 12.2 | |
2 | 0.83–1.10 | 0.14 | 37 | 75.5 | |
3 | 1.36–1.38 | 0.01 | 2 | 4.1 | |
4 or 5 | 2.42–2.88 | 0.23 | 2 | 4.1 | |
6 or 7 | 3.30 | - | 1 | 2.0 | |
SMN2 | 0 | 0 | - | 8 | 16.3 |
1 | 0.26–0.53 | 0.13 | 27 | 55.1 | |
1 or 2 (*) | 0.67–0.74 | - | 2 | 4.1 | |
2 | 0.82–1.20 | 0.19 | 7 | 14.3 | |
3 | 1.35–1.70 | 0.18 | 5 | 10.2 |