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Table 2 Averages of 2−ΔΔCT values and range per genotype in patients and carriers

From: Spinal muscular atrophy in Venezuela: quantitative analysis of SMN1 and SMN2 genes

Gene

Individuals (n)

Mean 2−∆∆CT

Ranges of values of 2−ΔΔCT

Estimated number of copies

SD

SMN1

Patients with deletion (13)

0

0

0

-

Patients without deletion (14)

1.14

0.84–1.71

2

0.57

Parents of patients with deletion (21)

0.43

0.16–0.66

1

0.26

Asymptomatic relatives with SMN1 deletion (2)

0

0

0

-

SMN2

Patients with SMN1 deletion (13)

1.43

0.26–2.60

3

1.17

Patients without SMN1 deletion (14)

0.78

0.20–1.37

2

0.58

Parents of patients with SMN1 deletion (21)

0.74

0.32–1.17

2

0.43

Asymptomatic relatives with SMN1 deletion (2)

1.98

1.73–2.23

4

0.25

  1. SD standard deviation