From: Spinal muscular atrophy in Venezuela: quantitative analysis of SMN1 and SMN2 genes
Gene | Individuals (n) | Mean 2−∆∆CT | Ranges of values of 2−ΔΔCT | Estimated number of copies | SD |
---|---|---|---|---|---|
SMN1 | Patients with deletion (13) | 0 | 0 | 0 | - |
Patients without deletion (14) | 1.14 | 0.84–1.71 | 2 | 0.57 | |
Parents of patients with deletion (21) | 0.43 | 0.16–0.66 | 1 | 0.26 | |
Asymptomatic relatives with SMN1 deletion (2) | 0 | 0 | 0 | - | |
SMN2 | Patients with SMN1 deletion (13) | 1.43 | 0.26–2.60 | 3 | 1.17 |
Patients without SMN1 deletion (14) | 0.78 | 0.20–1.37 | 2 | 0.58 | |
Parents of patients with SMN1 deletion (21) | 0.74 | 0.32–1.17 | 2 | 0.43 | |
Asymptomatic relatives with SMN1 deletion (2) | 1.98 | 1.73–2.23 | 4 | 0.25 |