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Fig. 1 | Egyptian Journal of Medical Human Genetics

Fig. 1

From: Assessment of vitamin D-binding protein (DBP) gene polymorphisms and their correlation with multiple sclerosis: a case-control study in a sample of the Syrian population

Fig. 1

Two separate PCR-RFLP 2%gel electrophoresis results for cases and controls. M: 100 bp molecular marker, 482 bp represents the uncut PCR product. Each case or control has two results depending on the different restriction enzymes used; H: HaeIII that cuts at 1S polymorphic site thus: homozygous wild type TT gets no cut fragments as in sample 36; while homozygous GG genotype gets two fragments (297, 185 bp) as in samples 37, 14, 15, whereas heterozygous TG gets three fragments (482,297,185) as in samples 38, 16, and 17. S: StyI which cleaves at 2 polymorphic sites as a result homozygous wild type CC gets no cut fragments as in samples 37, 38, 14, and 15. While heterozygous CA gets three fragments (482,308, and 174 bp) as in samples 36, 16, and 17

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