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Table 3 Association analysis results for rs7041 and rs4588 genotypes under different genetic models

From: Assessment of vitamin D-binding protein (DBP) gene polymorphisms and their correlation with multiple sclerosis: a case-control study in a sample of the Syrian population

rs7041 (c.1296 T > G)
Genetic model OR (95% CI) p value
Dominant TT vs. (TG+ GG) 0.03 ( 0.001 to 0.51) p = 0.01*
Recessive (TT + TG) vs. GG 6.00 (2.53to 14.20) p = 0.0001*
Over dominant (TT + GG )vs. TG 0.62 ( 0.286 to 1.38) p = 0.24
Homozygous codominant TT vs. GG 69.27 ( 3.89 to 1233.65) p = 0.0039*
Heterozygous codominant (TT vs. TG) 18.53 (1.056 to 325.28) p = 0.045*
Allele contrast (T vs. G) 2.80 (1.398 to 5.604) p = 0.0036*
rs4588 (c.1307C > A)
Genetic model OR (95% CI) p value
Dominant CC vs. (CA+ AA) 1.77 (0.74 to 4.20) p = 0.194
Recessive (CC + CA) vs. AA 0.33 (0.015 to 7.223) p = 0.4877
Over dominant (CC + AA) vs. CA 0.63 (0.267 to 1.52) p = 0.312
Homozygous codominant (CC vs. AA) 0.29 (0.013 to 6.29) p = 0.431
Heterozygous codominant (CC vs. CA) 0.61 (0.255 to 1.46) p = 0.268
Allele contrast (C vs. A) 0.65 (0.285 to 1.4955) p = 0.314
  1. *Statistically significant associations (p < 0.05)