Table 3 Association analysis results for rs7041 and rs4588 genotypes under different genetic models

Genetic model

OR (95% CI)

p value

Dominant TT vs. (TG+ GG)

0.03 ( 0.001 to 0.51)

p = 0.01*

Recessive (TT + TG) vs. GG

6.00 (2.53to 14.20)

p = 0.0001*

Over dominant (TT + GG )vs. TG

0.62 ( 0.286 to 1.38)

p = 0.24

Homozygous codominant TT vs. GG

69.27 ( 3.89 to 1233.65)

p = 0.0039*

Heterozygous codominant (TT vs. TG)

18.53 (1.056 to 325.28)

p = 0.045*

Allele contrast (T vs. G)

2.80 (1.398 to 5.604)

p = 0.0036*

Genetic model

OR (95% CI)

p value

Dominant CC vs. (CA+ AA)

1.77 (0.74 to 4.20)

p = 0.194

Recessive (CC + CA) vs. AA

0.33 (0.015 to 7.223)

p = 0.4877

Over dominant (CC + AA) vs. CA

0.63 (0.267 to 1.52)

p = 0.312

Homozygous codominant (CC vs. AA)

0.29 (0.013 to 6.29)

p = 0.431

Heterozygous codominant (CC vs. CA)

0.61 (0.255 to 1.46)

p = 0.268

Allele contrast (C vs. A)

0.65 (0.285 to 1.4955)

p = 0.314