Table 1 Demographic and clinical characteristics:
From: DNA integrity index as a potential molecular biomarker in colorectal cancer
| Parameter |
CRC patients (n = 90) |
Pathological controls (n = 30) |
Healthy controls (n = 30) |
|---|---|---|---|
|
Age (years) mean ± SD | 52 ± 9.5 | 50 ± 4.7 | 51 ± 5.9 |
|
Sex Male (%) Female (%) |
48/90 (53%) 42/90 (47%) |
12/30 (40%) 18/30 (60%) |
21/30 (70%) 9/30 (30%) |
|
Anemia Present (%) Absent (%) |
66/90 (73.3%) 24/90 (36.7%) |
12/30 (40%) 18/30 (60%) |
0/30 30/30 (100%) |
|
Constipation Present (%) Absent (%) |
57/90 (63.3%) 33/90 (36.7%) |
0/30 30/30 (100%) |
0/30 30/30 (100%) |
|
Bleeding per rectum Present (%) Absent (%) |
51/90 (56.7%) 39/90 (43.3%) |
3/30 (30%) 27/30 (90%) |
0/30 30/30 (100%) |
|
Palpable mass Present (%) Absent (%) |
3/90 (3.3%) 87/90 (96.7%) |
0/30 30 /30 (100%) |
0/30 30/30 (100%) |
|
Family history Present (%) Absent (%) |
21/90 (20%) 69/90 (80%) |
6/30 (20%) 24/30 (80%) |
0/30 30/30 (100%) |
|
Tumor size (mean ± SD) | 6.6 ± 1.9 | NA | NA |
|
Site of tumor Left (%) Right (%) Rectum (%) |
30/90 (33.3%) 33/90 (36.7%) 27/90 (30%) | NA | NA |
|
Grade of tumor 1 (%) 2 (%) 3 (%) |
9/90 (10%) 78/90 (86.7%) 3/90 (3.3%) | NA | NA |
|
TNM stage 1 (%) 2 (%) 3 (%) 4 (%) |
6/90 (6.7%) 21/90 (23.3%) 30/90 (33.3%) 33/90 (36.7%) | NA | NA |
|
Lymph nodes metastasis Present (%) Absent (%) |
30/90 (33.3%) 27/90 (30%) | NA | NA |
|
Distant metastasis Present (%) Absent (%) |
33/90 (36.7%) 57/90 (63.3%) | NA | NA |
