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Table 5 Genetic and laboratory characteristics of the patients regarding the immunophenotype characteristics and chromosomal abnormalities (numerical and structural) in ALL patients (during the second assessment)

From: COL1A1 polymorphism and neurological complications in pediatric acute lymphoblastic leukemia patients and their associations with altered bone mineral density

NO Immunophenotyping p Numerical abnormalities p Structural abnormalities p
Common
80
Pre b
20
+ve
40
−ve
60
+ve
60
−ve
40
G/G genotype 44 11 0.6 22 33 0.91 31 22 0.91
G/T genotype 26 8 13 21 21 13
T/T genotype 10 1 5 6 8 5
BMDLS − 2.00 ± 0.44 − 2.0 ± 0.11 0.4 − 2.11 ± 0.41 − 1.1 ± 0.01 0.2 − 2.0 ± 0.44 − 2.1 ± 0.48 0.6
PTH (ng/l), median (range) 46 (12–58) 49 (20–60) 0.5 48 (19–56) 50 (12–56) 0.9 50 (12–60) 53 (13–58) 0.4
Vit. D (nmol/l), median (range) 20 (12–35) 22 (15–30) 0.2 19 (14–31) 21 (13–35) 0.2 22 (14–34) 19 (12–35) 0.3
OC (ng/ml), median (range) 8 (8–20) 10 (9–18) 0.2 16 (8–18) 18 (9–20) 0.1 18 (8–17) 20 (14–20) 0.3
ALP (U/L), median (range) 71 (45–88) 67 (50–82) 0.3 65 (47–82) 69 (45–88) 0.1 73 (46–88) 70 (62–83) 0.2
  1. BMDLS bone mineral density of lumbar spine, PTH parathormon, Vit. D vitamin D, OC osteocalcin, ALP alkaline phosphatase