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Table 5 Genetic and laboratory characteristics of the patients regarding the immunophenotype characteristics and chromosomal abnormalities (numerical and structural) in ALL patients (during the second assessment)

From: COL1A1 polymorphism and neurological complications in pediatric acute lymphoblastic leukemia patients and their associations with altered bone mineral density

NO

Immunophenotyping

p

Numerical abnormalities

p

Structural abnormalities

p

Common

80

Pre b

20

+ve

40

−ve

60

+ve

60

−ve

40

G/G genotype

44

11

0.6

22

33

0.91

31

22

0.91

G/T genotype

26

8

13

21

21

13

T/T genotype

10

1

5

6

8

5

BMDLS

− 2.00 Âħ 0.44

− 2.0 Âħ 0.11

0.4

− 2.11 Âħ 0.41

− 1.1 Âħ 0.01

0.2

− 2.0 Âħ 0.44

− 2.1 Âħ 0.48

0.6

PTH (ng/l), median (range)

46 (12–58)

49 (20–60)

0.5

48 (19–56)

50 (12–56)

0.9

50 (12–60)

53 (13–58)

0.4

Vit. D (nmol/l), median (range)

20 (12–35)

22 (15–30)

0.2

19 (14–31)

21 (13–35)

0.2

22 (14–34)

19 (12–35)

0.3

OC (ng/ml), median (range)

8 (8–20)

10 (9–18)

0.2

16 (8–18)

18 (9–20)

0.1

18 (8–17)

20 (14–20)

0.3

ALP (U/L), median (range)

71 (45–88)

67 (50–82)

0.3

65 (47–82)

69 (45–88)

0.1

73 (46–88)

70 (62–83)

0.2

  1. BMDLS bone mineral density of lumbar spine, PTH parathormon, Vit. D vitamin D, OC osteocalcin, ALP alkaline phosphatase