Fig. 1
From: Detection of tmprss2-erg and tmprss2-egr1 gene fusion in prostate cancer from a Chinese population
Detection of TMPRSS2: ERG hybrid transcripts in needle biopsy samples from Chinese PCa patients. a Representative gel electrophoresis results of TMPRSS2: ERG gene fusion as detected by nested-PCR. M, molecular markers; lane 1, negative control; lanes 2–15, PCa samples; lane 16, BPH sample. b The PCR products were extracted from the gel, then subcloned into the pMD19-T vector. The hybrid transcripts were identified by sequencing. c The schematic structure of the TMPRSS2 (NM_005656.3) and ERG (NM_004449.4) transcripts, as well as their hybrid mRNAs. The coding region is shown in deep color